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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (59)Lit. (59) GO Terms (26)GO (26) Nucleotides (47)Nucl. (47) Proteins (31)Prot. (31) Interactants (579)Interact. (579) Wiki
XB-GENEPAGE-957719
???displayGene.symbol???:
 itk

???displayGene.name???: 
IL2-inducible T cell kinase

???displayGene.synonyms???
emt , lyk , psctk2 ( Nomenclature history )

???displayGene.geneFunction???
Tyrosine kinases

AI Protein Function :
itk encodes a Tec family non‑receptor tyrosine kinase that functions as a signaling molecule in T‑cell receptor pathways, phosphorylating downstream targets such as PLCγ1 to promote calcium mobilizatio...[+]


InterPro :
Kinase-like dom sf, Non-receptor tyrosine kinases, PH-like dom sf, PH domain, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
lymphoproliferative syndrome 1

MIM:
LYMPHOPROLIFERATIVE SYNDROME 1; LPFS1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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