Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (154)Lit. (154) GO Terms (78)GO (78) Nucleotides (501)Nucl. (501) Proteins (113)Prot. (113) Interactants (1070)Interact. (1070) Wiki
XB-GENEPAGE-478264
???displayGene.symbol???:
 tcf3

???displayGene.name???: 
transcription factor 3

???displayGene.synonyms???
bhlhb21 , E12 , e2a , itf1 , tcf-3 , tcfe2a [+] ( Nomenclature history )

???displayGene.geneFunction???
helix-loop-helix transcription factor

AI Protein Function :
tcf3 encodes a nuclear HMG‑box transcription factor of the TCF/LEF family that functions as a transcriptional repressor in canonical Wnt/β‑catenin signaling, regulating dorsal mesoderm formation, neura...[+]


InterPro :
HLH DNA-bd sf, bHLH dom, NeuroDiff E-box TFs

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
agammaglobulinemia 8A

MIM:
AGAMMAGLOBULINEMIA 8A, AUTOSOMAL DOMINANT; AGM8A

External Links:
GEO Series :
GSE56169.
1/6
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info