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Int J Parasitol Parasites Wildl
2021 Jun 08;15:231-237. doi: 10.1016/j.ijppaw.2021.06.001.
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Copepod consumption by amphibians and fish with implications for transmission of Dracunculus species.
Box EK, Cleveland CA, Garrett KB, Grunert RK, Hutchins K, Majewska AA, Thompson AT, Wyckoff ST, Ehlers C, Yabsley MJ.
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Parasitic nematodes in the genus Dracunculus have a complex life cycle that requires more than one host species in both aquatic and terrestrial habitats. The most well-studied species, Dracunculus medinensis, is the causative agent of human Guinea worm disease (dracunculiasis). There are several other Dracunculus species that infect non-human animals, primarily wildlife (reptiles and mammals). The classic route of D. medinensis transmission to humans is through the ingestion of water containing the intermediate host, a cyclopoid copepod, infected with third-stage larvae (L3s). However, many animal hosts (e.g., terrestrial snakes, dogs) of other Dracunculus sp. appear unlikely to ingest a large number of copepods while drinking. Therefore, alternative routes of infection (e.g., paratenic or transport hosts) may facilitate Dracunculus transmission to these species. To better understand the role of paratenic and transport hosts in Dracunculus transmission to animal definitive hosts, we compared copepod ingestion rates for aquatic species (fish, frogs [tadpoles and adults], and newts) which may serve as paratenic or transport hosts. We hypothesized that fish would consume more copepods than amphibians. Our findings confirm that African clawed frogs (Xenopus laevis) and fish consume copepods, but that fish ingest, on average, significantly higher numbers (68% [34/50]) than adult African clawed frogs (36% [18/50]) during a 24-h time period. Our results suggest that amphibians and fish may play a role in the transmission of Dracunculus to definitive hosts. Still, additional research is required to determine whether, in the wild, fish or frogs are serving as paratenic or transport hosts. If so, they may facilitate Dracunculus transmission. However, if these animals simply act as dead-end hosts or as means of copepod population control, they may decrease Dracunculus transmission.
Fig. 1. Average copepods ingested by animal type during the feeding trial. Bars represent average copepods ingested, error bars represent standard error, and dotted line shows average copepod loss in control trials. Significant differences (p < 0.05) determined by Tukey post-hoc contrasts are indicated by ‘a’, ‘b’, and ‘c’.
Fig. 2. Average copepods ingested by fish species during the feeding trial. Bars represent average copepods ingested, error bars represent standard error, and dotted line shows average copepod loss in control trials. Significant differences (p < 0.05) determined by Tukey post-hoc contrasts are indicated by ‘a’ and ‘b’.
Fig. 3. Average copepods ingested by tadpole species during the feeding trial. Bars represent average copepods ingested, error bars represent standard error, and dotted line shows average copepod loss in control trials. The lack of significant differences (p < 0.05) determined by Tukey post-hoc contrasts are indicated by ‘a’.
Cairncross,
Dracunculiasis (Guinea worm disease) and the eradication initiative.
2002, Pubmed
Cairncross,
Dracunculiasis (Guinea worm disease) and the eradication initiative.
2002,
Pubmed Cleveland,
Possible Role of Fish as Transport Hosts for Dracunculus spp. Larvae.
2017,
Pubmed Cleveland,
The wild world of Guinea Worms: A review of the genus Dracunculus in wildlife.
2018,
Pubmed Cleveland,
A search for tiny dragons (Dracunculus medinensis third-stage larvae) in aquatic animals in Chad, Africa.
2019,
Pubmed Cleveland,
Dracunculus Species in Meso-mammals from Georgia, United States, and Implications for the Guinea Worm Eradication Program in Chad, Africa.
2020,
Pubmed Crichton,
Observations on the seasonal prevalence, pathology and transmission of Dracunculus insignis (Nematoda: Dracunculoidea) in the raccoon (Procyon lotor (L.) in Ontario.
1977,
Pubmed Eberhard,
The role of tadpoles and frogs as paratenic hosts in the life cycle of Dracunculus insignis (Nematoda: Dracunculoidea).
1995,
Pubmed
,
Xenbase Eberhard,
The peculiar epidemiology of dracunculiasis in Chad.
2014,
Pubmed Eberhard,
Guinea Worm (Dracunculus medinensis) Infection in a Wild-Caught Frog, Chad.
2016,
Pubmed Eberhard,
Possible Role of Fish and Frogs as Paratenic Hosts of Dracunculus medinensis, Chad.
2016,
Pubmed Folmer,
DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates.
1994,
Pubmed Garrett,
Dogs and the classic route of Guinea Worm transmission: an evaluation of copepod ingestion.
2020,
Pubmed Guagliardo,
Guinea worm in domestic dogs in Chad: A description and analysis of surveillance data.
2020,
Pubmed Hothorn,
Simultaneous inference in general parametric models.
2008,
Pubmed McDonald,
Ecology of domestic dogs Canis familiaris as an emerging reservoir of Guinea worm Dracunculus medinensis infection.
2020,
Pubmed Muller,
Dracunculus and dracunculiasis.
1971,
Pubmed Muzzall,
Helminth infracommunities of the frogs Rana catesbeiana and Rana clamitans from Turkey Marsh, Michigan.
1991,
Pubmed Naust,
Concerning the structure and reproduction of the guinea worm (Filaria medinensis L.) by Aleksej Pavlovich Fedchenko, 1890.
1971,
Pubmed ONABAMIRO,
The diurnal migration of cyclops infected with the larvae of Dracunculus medinensis (Linnaeus), with some observations on the development of the larval worms.
1954,
Pubmed Richards,
Identifying correlates of Guinea worm (Dracunculus medinensis) infection in domestic dog populations.
2020,
Pubmed Ruiz-Tiben,
Dracunculiasis (Guinea worm disease) eradication.
2006,
Pubmed Toscano,
Deadly competition and life-saving predation: the potential for alternative stable states in a stage-structured predator-prey system.
2016,
Pubmed Uscanga,
Assessment of enzymatic efficiency on protein digestion in the tilapia Oreochromis niloticus.
2010,
Pubmed Williams,
Dracunculus infections in domestic dogs and cats in North America; an under-recognized parasite?
2018,
Pubmed Wilson-Aggarwal,
Ecology of domestic dogs (Canis familiaris) as a host for Guinea worm (Dracunculus medinensis) infection in Ethiopia.
2021,
Pubmed
