Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
In mature gametes and during the oocyte-to-embryo transition, transcription is generally silenced and gene expression is post-transcriptionally regulated. However, we recently discovered that major transcription can occur immediately after fertilization, prior to pronuclear fusion, and in the first cell division of the oocyte-to-embryo transition in the nematode Ascaris suum. We postulate that the balance between transcriptional and post-transcriptional regulation during the oocyte-to-embryo transition may largely be determined by cell cycle length and thus the time available for the genome to be transcribed.
Aanes,
Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition.
2011, Pubmed
Aanes,
Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition.
2011,
Pubmed Ali-Murthy,
An essential role for zygotic expression in the pre-cellular Drosophila embryo.
2013,
Pubmed Baugh,
Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome.
2003,
Pubmed Charlesworth,
Specificity factors in cytoplasmic polyadenylation.
2013,
Pubmed Dawid,
Composition and structure of chromosomal and amplified ribosomal DNA's of Xenopus laevis.
1970,
Pubmed
,
Xenbase De Renzis,
Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo.
2007,
Pubmed Giraldez,
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs.
2006,
Pubmed Gumienny,
Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.
1999,
Pubmed Hake,
CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation.
1994,
Pubmed
,
Xenbase Hamatani,
Dynamics of global gene expression changes during mouse preimplantation development.
2004,
Pubmed Harvey,
Identification of the zebrafish maternal and paternal transcriptomes.
2013,
Pubmed Heasman,
Patterning the early Xenopus embryo.
2006,
Pubmed
,
Xenbase Heyn,
The earliest transcribed zygotic genes are short, newly evolved, and different across species.
2014,
Pubmed Kalinka,
Gene expression divergence recapitulates the developmental hourglass model.
2010,
Pubmed Laugsch,
Differences in maternal supply and early development of closely related nematode species.
2004,
Pubmed Levin,
Developmental milestones punctuate gene expression in the Caenorhabditis embryo.
2012,
Pubmed Li,
Maternal control of early mouse development.
2010,
Pubmed Li,
The role of chromatin during transcription.
2007,
Pubmed Neff,
"Father knows best?".
2014,
Pubmed Paranjpe,
A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development.
2013,
Pubmed
,
Xenbase Pauli,
Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis.
2012,
Pubmed Powell-Coffman,
Onset of C. elegans gastrulation is blocked by inhibition of embryonic transcription with an RNA polymerase antisense RNA.
1996,
Pubmed Radford,
Translational control by cytoplasmic polyadenylation in Xenopus oocytes.
2008,
Pubmed
,
Xenbase Robertson,
The oocyte-to-embryo transition.
2013,
Pubmed Samanta,
The transcriptome of the sea urchin embryo.
2006,
Pubmed Schier,
The maternal-zygotic transition: death and birth of RNAs.
2007,
Pubmed Shermoen,
Progression of the cell cycle through mitosis leads to abortion of nascent transcripts.
1991,
Pubmed Skirkanich,
An essential role for transcription before the MBT in Xenopus laevis.
2011,
Pubmed
,
Xenbase Stebbins-Boaz,
Maskin is a CPEB-associated factor that transiently interacts with elF-4E.
1999,
Pubmed
,
Xenbase Stitzel,
Regulation of the oocyte-to-zygote transition.
2007,
Pubmed Stoeckius,
Global characterization of the oocyte-to-embryo transition in Caenorhabditis elegans uncovers a novel mRNA clearance mechanism.
2014,
Pubmed Swinburne,
Intron delays and transcriptional timing during development.
2008,
Pubmed Tadros,
SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.
2007,
Pubmed Tadros,
The maternal-to-zygotic transition: a play in two acts.
2009,
Pubmed Tan,
RNA sequencing reveals a diverse and dynamic repertoire of the Xenopus tropicalis transcriptome over development.
2013,
Pubmed
,
Xenbase Vasudevan,
Metazoan oocyte and early embryo development program: a progression through translation regulatory cascades.
2006,
Pubmed
,
Xenbase Wang,
Transcription in pronuclei and one- to four-cell embryos drives early development in a nematode.
2014,
Pubmed Wei,
A database of mRNA expression patterns for the sea urchin embryo.
2006,
Pubmed Xie,
Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species.
2010,
Pubmed Xue,
Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing.
2013,
Pubmed Yanai,
Mapping gene expression in two Xenopus species: evolutionary constraints and developmental flexibility.
2011,
Pubmed
,
Xenbase Young,
Control of the embryonic stem cell state.
2011,
Pubmed
