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XB-ART-18026
Comp Biochem Physiol B Biochem Mol Biol 1996 Jul 01;1143:313-5.
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The Xenopus laevis homologue of the 64-kDa subunit of cleavage stimulation factor.

Barbaux S, Seery LT, Schoenberg DR, Sellar GC, Whitehead AS.


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Cleavage stimulation factor (CstF) is composed of three subunits of 50, 64 and 77 kDa, respectively. We report here the identification of a cDNA clone from Xenopus laevis encoding a homologue of the 64-kDa subunit of human CstF. Comparative sequence analysis reveals that these two proteins are highly conserved with the exception of a unique repeat structure found in the human, but not in the X. laevis, protein. Analysis of expression of this mRNA during X. laevis tadpole development indicates a requirement for this protein throughout all stages of development.

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