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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (28)GO (28) Nucleotides (296)Nucl. (296) Proteins (54)Prot. (54) Interactants (132)Interact. (132) Wiki
XB-GENEPAGE-998806
???displayGene.symbol???:
 atic

???displayGene.name???: 
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

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( Nomenclature history )

???displayGene.geneFunction???
AICAR transformylase/IMP cyclohydrolase/methylglyoxal synthase

AI Protein Function :
atic encodes a bifunctional enzyme with AICAR transformylase and IMP cyclohydrolase activities that catalyze the final steps of de novo purine nucleotide biosynthesis. The protein is a soluble cytoplas...[+]


InterPro :
MGS-like dom sf, AICAR Tfase insert dom sf, AICAR Tfase dup dom sf, PurH-like, [+]

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Diseases: 


MIM:
AICA-RIBOSIDURIA DUE TO ATIC DEFICIENCY

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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