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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (17)GO (17) Nucleotides (109)Nucl. (109) Proteins (52)Prot. (52) Interactants (102)Interact. (102) Wiki
XB-GENEPAGE-998505
???displayGene.symbol???:
 lztr1

???displayGene.name???: 
leucine zipper like post translational regulator 1

???displayGene.synonyms???
LOC108695673 ( Nomenclature history )

???displayGene.geneFunction???
Uncharacterized conserved protein, contains kelch repeat

AI Protein Function :
lztr1 encodes a BTB‑Kelch domain protein that functions as an adaptor in a cullin‑3 ubiquitin ligase complex targeting Ras for ubiquitination and regulates MAPK signaling. The protein is detected in th...[+]


InterPro :
BTB/POZ dom, Kelch 1, SKP1/BTB/POZ sf, Kelch-typ b-propeller, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Noonan syndrome 2 [+]

MIM:
SCHWANNOMATOSIS 2; SWN2 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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