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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (68)GO (68) Nucleotides (93)Nucl. (93) Proteins (44)Prot. (44) Interactants (149)Interact. (149) Wiki
XB-GENEPAGE-998024
???displayGene.symbol???:
 pcsk9

???displayGene.name???: 
proprotein convertase subtilisin/kexin type 9

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Subtilisin-related protease/Vacuolar protease B

AI Protein Function :
pcsk9 encodes a secreted serine protease that modulates low‑density lipoprotein receptor levels; the protein is synthesized as a zymogen, processed in the endoplasmic reticulum and Golgi, and secreted ...[+]


InterPro :
S8pro/Inhibitor I9 sf, PCSK9 C3, PCSK9 ProteinaseK-like, Peptidase S8/S53 dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


MIM:
HYPERCHOLESTEROLEMIA, FAMILIAL, 3; FHCL3

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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