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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (7)Lit. (7) GO Terms (25)GO (25) Nucleotides (96)Nucl. (96) Proteins (40)Prot. (40) Interactants (45)Interact. (45) Wiki
XB-GENEPAGE-995290
???displayGene.symbol???:
 apc2

???displayGene.name???: 
adenomatosis polyposis coli 2

???displayGene.synonyms???
apcl , LOC108704666 ( Nomenclature history )

???displayGene.geneFunction???
Beta-catenin-binding protein APC, contains ARM repeats

AI Protein Function :
apc2 encodes a core subunit of the anaphase‑promoting complex/cyclosome, an E3 ubiquitin ligase that mediates ubiquitination of cyclin B, securin and other cell‑cycle regulators to control mitotic exit...[+]


InterPro :
APC basic dom, APC dom, Apc fam, APC N, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Sotos syndrome [+]

MIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 74; MRT74

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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