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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (39)GO (39) Nucleotides (151)Nucl. (151) Proteins (56)Prot. (56) Interactants (103)Interact. (103) Wiki
XB-GENEPAGE-993454
???displayGene.symbol???:
 phf8

???displayGene.name???: 
PHD finger protein 8

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( Nomenclature history )

???displayGene.geneFunction???
F-box protein JEMMA and related proteins with JmjC, PHD, F-box and LRR domains

AI Protein Function :
phf8 encodes a nuclear JmjC‑domain histone demethylase that removes methyl groups from H3K9me2/1 and H4K20me1, acting as a transcriptional regulator; expression is detected in the neural plate, neural ...[+]


InterPro :
Znf PHD, JHD, JmjC dom, Zinc finger PHD-type CS, [+]

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Diseases: 


Disease Ontology:
syndromic X-linked intellectual disability Siderius type

MIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED, SYNDROMIC, SIDERIUS TYPE; MRXSSD

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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