Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (17)GO (17) Nucleotides (311)Nucl. (311) Proteins (47)Prot. (47) Interactants (58)Interact. (58) Wiki
XB-GENEPAGE-992131
???displayGene.symbol???:
 mthfd1

???displayGene.name???: 
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
C1-tetrahydrofolate synthase

AI Protein Function :
mthfd1 is a cytosolic metabolic enzyme that catalyzes the NADP‑dependent oxidation of 5,10‑methylenetetrahydrofolate to 5,10‑methenyltetrahydrofolate and the subsequent cyclohydrolase conversion to 10‑...[+]


InterPro :
THF DH/CycHdrlase NAD-bd dom, Formate THF ligase CS, P-loop NTPase, NAD(P)-bd dom sf, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
neural tube defect

MIM:
NEURAL TUBE DEFECTS, FOLATE-SENSITIVE; NTDFS [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info