Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (14)GO (14) Nucleotides (60)Nucl. (60) Proteins (29)Prot. (29) Interactants (61)Interact. (61) Wiki
XB-GENEPAGE-991848
???displayGene.symbol???:
 isca2

???displayGene.name???: 
iron-sulfur cluster assembly 2

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Mitochondrial Fe-S cluster biosynthesis protein ISA2 (contains a HesB-like domain)

AI Protein Function :
isca2 encodes a mitochondrial iron‑sulfur cluster assembly protein that facilitates the formation of [2Fe‑2S] and [4Fe‑4S] clusters and supports mitochondrial iron homeostasis. The protein is localized...[+]


InterPro :
HesB-like dom sf, FeS cluster insertion, FeS cluster insertion CS, FeS biogenesis

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
multiple mitochondrial dysfunctions syndrome 4

MIM:
MULTIPLE MITOCHONDRIAL DYSFUNCTIONS SYNDROME 4; MMDS4

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info