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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (7)Lit. (7) GO Terms (107)GO (107) Nucleotides (225)Nucl. (225) Proteins (67)Prot. (67) Interactants (212)Interact. (212) Wiki
XB-GENEPAGE-989848
???displayGene.symbol???:
 eif2ak3

???displayGene.name???: 
eukaryotic translation initiation factor 2 alpha kinase 3

???displayGene.synonyms???
LOC108697591 ( Nomenclature history )

???displayGene.geneFunction???
eIF-2alpha kinase PEK/EIF2AK3

AI Protein Function :
eif2ak3 encodes an endoplasmic reticulum‑resident serine/threonine‑protein kinase that phosphorylates eIF2α to attenuate global protein synthesis during the unfolded protein response, activates downstr...[+]


InterPro :
WD40/YVTN repeat-like dom sf, Protein kinase ATP BS, Ser/Thr kinase AS, Kinase-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Wolcott-Rallison syndrome

MIM:
EPIPHYSEAL DYSPLASIA, MULTIPLE, WITH EARLY-ONSET DIABETES MELLITUS

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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