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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (9)Lit. (9) GO Terms (41)GO (41) Nucleotides (98)Nucl. (98) Proteins (48)Prot. (48) Interactants (103)Interact. (103) Wiki
XB-GENEPAGE-988967
???displayGene.symbol???:
 apaf1

???displayGene.name???: 
apoptotic peptidase activating factor 1

???displayGene.synonyms???
apaf-1 ( Nomenclature history )

???displayGene.geneFunction???
apoptosis/apoptosome scaffold protein with WD-40 domains, caspase recruitment domain (CARD), and an ATPase domain

AI Protein Function :
apaf1 is a cytosolic apoptotic adaptor protein that assembles the apoptosome after binding cytochrome c and dATP, thereby activating caspase‑9 and driving programmed cell death. It mediates cytochrome ...[+]


InterPro :
WH-like DNA-bd sf, Apaf-1, WD40 repeat CS, DEATH-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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