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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (50)GO (50) Nucleotides (69)Nucl. (69) Proteins (39)Prot. (39) Interactants (4)Interact. (4) Wiki
XB-GENEPAGE-988818
???displayGene.symbol???:
 abcb11.2

???displayGene.name???: 
ATP binding cassette subfamily B member 11, gene 2

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( Nomenclature history )

???displayGene.geneFunction???
Multidrug/pheromone exporter, ABC superfamily

AI Protein Function :
abcb11.2 encodes a membrane‑bound ATP‑binding cassette transporter that mediates ATP‑dependent export of bile salts; it functions as the bile salt export pump (BSEP) in hepatocytes, localizing to the c...[+]


InterPro :
AAA+ ATPase, ABC1 TM dom, ABC1 TM sf, ABC transporter-like ATP-bd, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
intrahepatic cholestasis [+]

MIM:
CHOLESTASIS, PROGRESSIVE FAMILIAL INTRAHEPATIC, 2; PFIC2 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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