Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (11)Lit. (11) GO Terms (87)GO (87) Nucleotides (1174)Nucl. (1174) Proteins (55)Prot. (55) Interactants (185)Interact. (185) Wiki
XB-GENEPAGE-983840
???displayGene.symbol???:
 atf4

???displayGene.name???: 
activating transcription factor 4

???displayGene.synonyms???
atf-4 , atf4-a , atf4-b , creb-2 , creb2 , taxreb67 [+] ( Nomenclature history )

???displayGene.geneFunction???
basic-leucine zipper (bZIP) transcription factor

AI Protein Function :
atf4 encodes a nuclear bZIP transcription factor that binds CRE/ATF elements to regulate genes of the unfolded protein response, amino‑acid biosynthesis, oxidative‑stress defenses and apoptosis, and it...[+]


InterPro :
bZIP, bZIP sf

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
microphthalmia

External Links:
1/4
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info