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Summary Expression Expr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (11)GO (11) Nucleotides (129)Nucl. (129) Proteins (41)Prot. (41) Interactants (37)Interact. (37) Wiki
XB-GENEPAGE-980230
???displayGene.symbol???:
 c8a

???displayGene.name???: 
complement C8 alpha chain

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( Nomenclature history )

???displayGene.geneFunction???
participates in the formation of the membrane attack complex during immune response

AI Protein Function :
c8a encodes a secreted complement component that forms part of the membrane attack complex, binding to C5b‑7 and contributing to target cell lysis; the protein is localized to the extracellular space a...[+]


InterPro :
TSP1 rpt sf, LDL receptor-like sf, LDLR class-A CS, MACPF, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
type I complement component 8 deficiency

MIM:
COMPLEMENT COMPONENT 8 DEFICIENCY, TYPE I; C8D1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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