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Summary Expression Expr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (13)GO (13) Nucleotides (1309)Nucl. (1309) Proteins (55)Prot. (55) Interactants (461)Interact. (461) Wiki
XB-GENEPAGE-976314
???displayGene.symbol???:
 idh2

???displayGene.name???: 
isocitrate dehydrogenase 2 (NADP+), mitochondrial

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( Nomenclature history )

???displayGene.geneFunction???
NADP-dependent isocitrate dehydrogenase

AI Protein Function :
idh2 encodes a mitochondrial NADP‑dependent isocitrate dehydrogenase that catalyzes the conversion of isocitrate to α‑ketoglutarate with production of NADPH, participating in the tricarboxylic acid cyc...[+]


InterPro :
Isocitrate DH NADP, IsoCit/isopropylmalate DH CS, IsoPropMal-DH-like dom

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
D-2-hydroxyglutaric aciduria [+]

MIM:
D-2-HYDROXYGLUTARIC ACIDURIA 2; D2HGA2

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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