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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (24)GO (24) Nucleotides (336)Nucl. (336) Proteins (62)Prot. (62) Interactants (28)Interact. (28) Wiki
XB-GENEPAGE-973906
???displayGene.symbol???:
 crbn

???displayGene.name???: 
cereblon

???displayGene.synonyms???
cereblon , mrt2a ( Nomenclature history )

???displayGene.geneFunction???
Predicted ATP-dependent protease PIL, contains LON domain

AI Protein Function :
crbn encodes a substrate receptor of a cullin‑4‑ddb1 E3 ubiquitin ligase complex that directs ubiquitination of target proteins, regulates protein stability during early embryogenesis, and influences n...[+]


InterPro :
PUA-like sf, CULT, Yippee/Mis18/Cereblon, Lon substr-bd, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
autosomal recessive intellectual developmental disorder [+]

MIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 2; MRT2

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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