XB-GENEPAGE-972563
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fto
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FTO alpha-ketoglutarate dependent dioxygenase
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(
Nomenclature history )
AI Protein Function
:
fto encodes a Fe(II)- and 2‑oxoglutarate‑dependent dioxygenase that demethylates N6‑methyladenosine in nuclear RNA, functioning as an mRNA demethylase. The protein is primarily nuclear but is also foun...[+]
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Diseases:
Disease Ontology:
obesity
MIM:
OBESITY
External Links:
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Symbol legend:
