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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (17)GO (17) Nucleotides (117)Nucl. (117) Proteins (49)Prot. (49) Interactants (451)Interact. (451) Wiki
XB-GENEPAGE-967300
???displayGene.symbol???:
 mccc1

???displayGene.name???: 
methylcrotonoyl-CoA carboxylase 1

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
3-Methylcrotonyl-CoA carboxylase, biotin-containing subunit/Propionyl-CoA carboxylase, alpha chain/Acetyl-CoA carboxylase, biotin carboxylase subunit

AI Protein Function :
mccc1 encodes a mitochondrial biotin‑dependent carboxylase that catalyzes the ATP‑dependent carboxylation of 3‑methylcrotonyl‑CoA, a step in leucine catabolism. The protein localizes to the mitochondri...[+]


InterPro :
Biotin lipoyl, Biotin COase C, Single hybrid motif, Biotin carboxylation dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
3-methylcrotonyl-CoA carboxylase deficiency [+]

MIM:
3-METHYLCROTONYL-CoA CARBOXYLASE 1 DEFICIENCY; MCC1D

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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