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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (44)GO (44) Nucleotides (133)Nucl. (133) Proteins (54)Prot. (54) Interactants (112)Interact. (112) Wiki
XB-GENEPAGE-966857
???displayGene.symbol???:
 setx

???displayGene.name???: 
senataxin

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
tRNA-splicing endonuclease positive effector (SEN1)

AI Protein Function :
setx encodes a DNA/RNA helicase that participates in transcription termination and resolves R‑loop structures, contributing to genome stability. The protein localizes to the nucleus and nucleolus. Expr...[+]


InterPro :
DNA2/NAM7-like AAA, Helicase Sen1 N, DNA2/NAM7 AAA 11, P-loop NTPase, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
spinocerebellar ataxia with axonal neuropathy 2 [+]

MIM:
AMYOTROPHIC LATERAL SCLEROSIS 4, JUVENILE; ALS4 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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