XB-GENEPAGE-966696
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stub1
???displayGene.name???:
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
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Nomenclature history )
???displayGene.geneFunction???
Chaperone-dependent E3 ubiquitin protein ligase (contains TPR repeats)
AI Protein Function
:
stub1 encodes a cytoplasmic and nuclear E3 ubiquitin ligase that acts as a co‑chaperone for Hsp70 and Hsp90, promotes ubiquitination and proteasomal degradation of misfolded proteins, and modulates sig...[+]
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Diseases:
Disease Ontology:
autosomal recessive spinocerebellar ataxia 16
MIM:
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 16; SCAR16
External Links:
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