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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (22)GO (22) Nucleotides (171)Nucl. (171) Proteins (38)Prot. (38) Interactants (57)Interact. (57) Wiki
XB-GENEPAGE-961681
???displayGene.symbol???:
 vps45

???displayGene.name???: 
vacuolar protein sorting 45 homolog

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( Nomenclature history )

???displayGene.geneFunction???
Vacuolar sorting protein VPS45/Stt10 (Sec1 family)

AI Protein Function :
vps45 encodes a Sec1/Munc18 family protein that functions in vesicle‑mediated transport, specifically regulating endosome‑to‑lysosome trafficking. It localizes to the cytosol and endosomal membranes. E...[+]


InterPro :
Sec1-like, Sec1-like sf, Sec-1-like dom2, Sec-1-like dom1, [+]

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Diseases: 


Disease Ontology:
severe congenital neutropenia [+]

MIM:
NEUTROPENIA, SEVERE CONGENITAL, 5, AUTOSOMAL RECESSIVE; SCN5

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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