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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (7)GO (7) Nucleotides (48)Nucl. (48) Proteins (30)Prot. (30) Interactants (0)Interact. (0) Wiki
XB-GENEPAGE-961003
???displayGene.symbol???:
 nxnl1

???displayGene.name???: 
nucleoredoxin like 1

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( Nomenclature history )

???displayGene.geneFunction???
Thioredoxin, nucleoredoxin and related proteins. Retinitis pigmentosa (RP) is a disease that leads to blindness by degeneration of cone photoreceptors. Rods produce factors required for cone viability. The protein encoded by this gene is one of those factors and is similar to a truncated form of thioredoxin. This gene has been proposed to have therapeutic value against RP. [provided by RefSeq, Dec 2015]

AI Protein Function :
nxnl1 encodes a secreted trophic factor that supports cone photoreceptor survival and a thioredoxin‑like isoform with redox activity. The secreted form functions as a ligand that enhances glucose uptak...[+]


InterPro :
RdCVF, Thioredoxin-like fold, Thioredoxin-like sf

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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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