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Summary Expression Expr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (13)GO (13) Nucleotides (63)Nucl. (63) Proteins (36)Prot. (36) Interactants (34)Interact. (34) Wiki
XB-GENEPAGE-958504
???displayGene.symbol???:
 map3k8

???displayGene.name???: 
mitogen-activated protein kinase kinase kinase 8

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
map3k8 encodes a serine/threonine protein kinase that functions as a MAP3K in the MAPK signaling cascade, phosphorylating downstream MAP2Ks to activate ERK1/2 and NF‑κB pathways. It acts as a signaling...[+]


InterPro :
Kinase-like dom sf, MAP kinase kinase kinase, Prot kinase dom, Ser/Thr kinase AS

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Diseases: 


Disease Ontology:
lung cancer

MIM:
LUNG CANCER

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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