Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (43)GO (43) Nucleotides (165)Nucl. (165) Proteins (43)Prot. (43) Interactants (154)Interact. (154) Wiki
XB-GENEPAGE-957784
???displayGene.symbol???:
 keap1

???displayGene.name???: 
kelch like ECH associated protein 1

???displayGene.synonyms???
INrf2 , klhl19 ( Nomenclature history )

???displayGene.geneFunction???
Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes

AI Protein Function :
keap1 encodes a cytoplasmic adaptor protein that assembles a Cul3‑Rbx1 ubiquitin ligase complex to target the transcription factor nrf2 for proteasomal degradation, thereby acting as a negative regulat...[+]


InterPro :
KEAP1, BTB/POZ dom, BTB-kelch protein, Kelch 1, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info