Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (23)Lit. (23) GO Terms (45)GO (45) Nucleotides (328)Nucl. (328) Proteins (53)Prot. (53) Interactants (383)Interact. (383) Wiki
XB-GENEPAGE-957582
???displayGene.symbol???:
 smc3

???displayGene.name???: 
structural maintenance of chromosomes 3

???displayGene.synonyms???
xsmc3 ( Nomenclature history )

???displayGene.geneFunction???
Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3)

AI Protein Function :
smc3 encodes a core component of the cohesin complex that mediates sister chromatid cohesion during S phase and mitosis, facilitates DNA double‑strand break repair, contributes to chromosome condensati...[+]


InterPro :
P-loop NTPase, RecF/RecN/SMC N, SMC, SMC3 ABC euk, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
Cornelia de Lange syndrome

MIM:
CORNELIA DE LANGE SYNDROME 3 WITH OR WITHOUT MIDLINE BRAIN DEFECTS; CDLS3

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info