Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (37)GO (37) Nucleotides (72)Nucl. (72) Proteins (40)Prot. (40) Interactants (14)Interact. (14) Wiki
XB-GENEPAGE-956408
???displayGene.symbol???:
 zap70

???displayGene.name???: 
zeta chain of T cell receptor associated protein kinase 70

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Tyrosine kinases

AI Protein Function :
zap70 is a cytoplasmic protein‑tyrosine kinase that functions as a signaling molecule in T‑cell receptor pathways, phosphorylating LAT and SLP‑76 to drive MAPK activation and calcium flux; it is recrui...[+]


InterPro :
Tyr kinase non-rcpt SYK/ZAP70, Kinase-like dom sf, SH2 dom sf, SYK/ZAP-70 N SH2, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
immunodeficiency 48

MIM:
IMMUNODEFICIENCY 48; IMD48 [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info