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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (57)GO (57) Nucleotides (132)Nucl. (132) Proteins (44)Prot. (44) Interactants (83)Interact. (83) Wiki
XB-GENEPAGE-955076
???displayGene.symbol???:
 ncstn

???displayGene.name???: 
nicastrin

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( Nomenclature history )

???displayGene.geneFunction???
Transmembrane glycoprotein nicastrin

AI Protein Function :
ncstn encodes a type I transmembrane protein that is a core component of the γ‑secretase complex, mediating intramembrane proteolysis of Notch receptors and amyloid precursor protein and thereby regula...[+]


InterPro :
Nicastrin, Ncstrn small

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Diseases: 


Disease Ontology:
hidradenitis suppurativa

MIM:
ACNE INVERSA, FAMILIAL, 1; ACNINV1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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