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Summary Expression Expr. PhenotypesPheno. Gene Literature (13)Lit. (13) GO Terms (19)GO (19) Nucleotides (46)Nucl. (46) Proteins (30)Prot. (30) Interactants (342)Interact. (342) Wiki
XB-GENEPAGE-952684
???displayGene.symbol???:
 rnf43

???displayGene.name???: 
ring finger protein 43

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
E3 ubiquitin ligase

AI Protein Function :
rnf43 encodes a transmembrane E3 ubiquitin ligase that acts as a negative regulator of Wnt signaling by promoting ubiquitination and internalization of Frizzled receptors; the protein localizes to the ...[+]


InterPro :
Znf RING, Znf RING/FYVE/PHD, ZNRF-3 ecto, ZNRF3 Arkadia E3 ligases

???displayGene.geneInteractants???
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Diseases: 


MIM:
SESSILE SERRATED POLYPOSIS CANCER SYNDROME; SSPCS

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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