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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (1)Lit. (1) GO Terms (7)GO (7) Nucleotides (88)Nucl. (88) Proteins (61)Prot. (61) Interactants (65)Interact. (65) Wiki
XB-GENEPAGE-949772
???displayGene.symbol???:
 arhgef6

???displayGene.name???: 
Rac/Cdc42 guanine nucleotide exchange factor 6

???displayGene.synonyms???
alphaPIX , cool-2 , cool2 , mrx46 , pixa [-] ( Nomenclature history )

???displayGene.geneFunction???
Guanine nucleotide exchange factor

AI Protein Function :
Arhgef6 is a signaling molecule classified as a Rho guanine nucleotide exchange factor that activates Rac1 and Cdc42. It localizes to the plasma membrane and cytoplasmic puncta, often at focal adhesion...[+]


InterPro :
SH3-like dom sf, CH-domain, GEF CC, DH-domain, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
non-syndromic X-linked intellectual disability

MIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED 46; XLID46

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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