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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (23)GO (23) Nucleotides (94)Nucl. (94) Proteins (42)Prot. (42) Interactants (25)Interact. (25) Wiki
XB-GENEPAGE-948712
???displayGene.symbol???:
 mlkl

???displayGene.name???: 
mixed lineage kinase domain-like

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs

AI Protein Function :
mlkl encodes a pseudokinase that functions as the terminal effector of necroptosis, mediating plasma membrane rupture after phosphorylation by ripk3; it localizes to the cytoplasm and translocates to t...[+]


InterPro :
Ser-Thr/Tyr kinase cat dom, Kinase-like dom sf, Prot kinase dom, Adaptor Cbl N dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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