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Summary Expression Expr. PhenotypesPheno. Gene Literature (21)Lit. (21) GO Terms (30)GO (30) Nucleotides (81)Nucl. (81) Proteins (40)Prot. (40) Interactants (475)Interact. (475) Wiki
XB-GENEPAGE-946234
???displayGene.symbol???:
 rspo2

???displayGene.name???: 
R-spondin 2

???displayGene.synonyms???
CRISTIN2 , R-spondin 2 ( Nomenclature history )

???displayGene.geneFunction???
Subtilisin-like proprotein convertase

AI Protein Function :
Rspo2 encodes a secreted signaling protein that acts as a potent enhancer of canonical Wnt/β‑catenin signaling; it is required for proper limb bud outgrowth and craniofacial morphogenesis, influencing ...[+]


InterPro :
TSP1 rpt sf, Furin repeat, Growth fac rcpt cys sf, TSP1 rpt, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
tetraamelia syndrome 2

MIM:
HUMEROFEMORAL HYPOPLASIA WITH RADIOTIBIAL RAY DEFICIENCY; HHRRD [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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