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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (57)GO (57) Nucleotides (156)Nucl. (156) Proteins (62)Prot. (62) Interactants (444)Interact. (444) Wiki
XB-GENEPAGE-943657
???displayGene.symbol???:
 optn

???displayGene.name???: 
optineurin

???displayGene.synonyms???
( Nomenclature history )

???displayGene.geneFunction???
ER-Golgi vesicle tethering

AI Protein Function :
optn encodes a cytoplasmic signaling adaptor protein that binds ubiquitin, participates in autophagy and negatively regulates NF‑κB signaling, localizes to the cytoplasm, Golgi apparatus and vesicular ...[+]


InterPro :
NEMO N, CC2-LZ dom, NEMO ZF, Optineurin/NFkB EssMod

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
amyotrophic lateral sclerosis type 12 [+]

MIM:
GLAUCOMA, PRIMARY OPEN ANGLE; POAG [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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