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Summary Expression Expr. PhenotypesPheno. Gene Literature (44)Lit. (44) GO Terms (64)GO (64) Nucleotides (122)Nucl. (122) Proteins (47)Prot. (47) Interactants (371)Interact. (371) Wiki
XB-GENEPAGE-943035
???displayGene.symbol???:
 nbn

???displayGene.name???: 
nibrin

???displayGene.synonyms???
nbs , nbs1 , nibrin ( Nomenclature history )

???displayGene.geneFunction???
Transcription initiation factor IIF, large subunit (RAP74)

AI Protein Function :
nbn encodes a nuclear DNA‑repair protein that is a core component of the MRN complex, mediating detection and processing of DNA double‑strand breaks, activation of ATM signaling, cell‑cycle checkpoint ...[+]


InterPro :
SMAD FHA dom sf, Nibrin met, BRCT dom sf, Nibrin BRCT2, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
aplastic anemia [+]

MIM:
APLASTIC ANEMIA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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