XB-GENEPAGE-922525
???displayGene.symbol???:
vps11
???displayGene.name???:
VPS11, CORVET/HOPS core subunit
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(
Nomenclature history )
???displayGene.geneFunction???
ubiquitin-protein ligase
AI Protein Function
:
vps11 is a component of the HOPS tethering complex that mediates membrane fusion between late endosomes and lysosomes, facilitating autophagosome‑lysosome fusion and endosome‑lysosome trafficking. The ...[+]
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Diseases:
Disease Ontology:
hypomyelinating leukodystrophy 12
MIM:
LEUKODYSTROPHY, HYPOMYELINATING, 12; HLD12
External Links:
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