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Summary Expression Expr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (69)GO (69) Nucleotides (220)Nucl. (220) Proteins (74)Prot. (74) Interactants (55)Interact. (55) Wiki
XB-GENEPAGE-922515
???displayGene.symbol???:
 trio

???displayGene.name???: 
trio Rho guanine nucleotide exchange factor

???displayGene.synonyms???
arhgef23 , tgat ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
trio encodes a Rho guanine nucleotide‑exchange factor that activates Rac1 and RhoA, regulating actin cytoskeleton dynamics; it functions in neuronal migration, axon guidance, neural crest cell migratio...[+]


InterPro :
CRAL-TRIO dom, Spectrin/alpha-actinin, Ig I-set, DBL dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
autosomal dominant intellectual developmental disorder 44

MIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL DOMINANT 44, WITH MICROCEPHALY; M

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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