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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (29)GO (29) Nucleotides (275)Nucl. (275) Proteins (43)Prot. (43) Interactants (46)Interact. (46) Wiki
XB-GENEPAGE-921427
???displayGene.symbol???:
 aph1a

???displayGene.name???: 
aph-1 homolog A, gamma secretase subunit

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( Nomenclature history )

???displayGene.geneFunction???
membrane protein, component of gamma-secretase complex

AI Protein Function :
aph1a encodes a membrane‑bound component of the γ‑secretase complex that mediates intramembrane cleavage of Notch receptors and other substrates, thereby modulating Notch signaling. The protein localiz...[+]


InterPro :
Aph-1

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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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