Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (36)Lit. (36) GO Terms (63)GO (63) Nucleotides (50)Nucl. (50) Proteins (29)Prot. (29) Interactants (167)Interact. (167) Wiki
XB-GENEPAGE-876705
???displayGene.symbol???:
 smad6.2

???displayGene.name???: 
SMAD family member 6, gene 2

???displayGene.synonyms???
Xsmad6 ( Nomenclature history )

???displayGene.geneFunction???
signal transduction, TGF-beta pathway

AI Protein Function :
smad6.2 is an inhibitory smad signaling molecule that antagonizes bone morphogenetic protein (BMP) signaling by competing with receptor‑regulated smads and preventing phosphorylation of SMAD1/5/8; it m...[+]


InterPro :
MAD homology MH1, SMAD FHA dom sf, SMAD MH1 sf, SMAD dom Dwarfin-type, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
aortic valve stenosis [+]

MIM:
AORTIC VALVE DISEASE 2; AOVD2 [+]

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info