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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (51)GO (51) Nucleotides (38)Nucl. (38) Proteins (25)Prot. (25) Interactants (21)Interact. (21) Wiki
XB-GENEPAGE-855712
???displayGene.symbol???:
 mstn.2

???displayGene.name???: 
myostatin, gene 2

???displayGene.synonyms???
gdf8 , growth differentiation factor 8 , LOC108701488 ( Nomenclature history )

???displayGene.geneFunction???
transforming growth factor beta and bone morphogenetic protein related peptide

AI Protein Function :
mstn.2 encodes a secreted TGF‑β family signaling molecule that acts as a negative regulator of skeletal muscle growth; it limits myoblast proliferation and promotes differentiation, thereby controlling...[+]


InterPro :
Cystine-knot cytokine, TGF-b C, TGF-b propeptide, TGF-beta-rel, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
myostatin-related muscle hypertrophy

MIM:
MUSCLE HYPERTROPHY; MSLHP

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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