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Summary Expression Expr. PhenotypesPheno. Gene Literature (3)Lit. (3) GO Terms (108)GO (108) Nucleotides (163)Nucl. (163) Proteins (67)Prot. (67) Interactants (62)Interact. (62) Wiki
XB-GENEPAGE-854876
???displayGene.symbol???:
 psen2

???displayGene.name???: 
presenilin 2

???displayGene.synonyms???
presenilin-alpha , presenilin-beta , ps-a , ps-alpha , ps-b , ps-beta [+] ( Nomenclature history )

???displayGene.geneFunction???
intracellular signaling

AI Protein Function :
psen2 is a membrane‑bound aspartyl protease that functions as the catalytic subunit of the γ‑secretase complex, mediating intramembrane cleavage of substrates such as Notch receptors and amyloid precur...[+]


InterPro :
Presenilin C, Peptidase A22A, Preselin/SPP

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Alzheimer's disease 4 [+]

MIM:
ALZHEIMER DISEASE 4; AD4 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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