Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (23)GO (23) Nucleotides (135)Nucl. (135) Proteins (34)Prot. (34) Interactants (50)Interact. (50) Wiki
XB-GENEPAGE-854508
???displayGene.symbol???:
 cd247

???displayGene.name???: 
CD247 molecule

???displayGene.synonyms???
cd247-a , cd247-b , cd3z , CD3Z antigen, zeta polypeptide , cd3-zeta , tcrz [+] ( Nomenclature history )

???displayGene.geneFunction???
cell surface receptor linked signal transduction

AI Protein Function :
cd247 encodes the T‑cell receptor ζ chain, a transmembrane signaling subunit of the CD3 complex that participates in T‑cell activation; it contains multiple ITAM motifs that become phosphorylated upon ...[+]


InterPro :
CD3 zeta/IgE Fc rcpt gamma, Phos immunorcpt sig ITAM, T-cell CD3 zeta

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
immunodeficiency 25

MIM:
IMMUNODEFICIENCY 25; IMD25

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info