Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Expr. PhenotypesPheno. Gene Literature (17)Lit. (17) GO Terms (34)GO (34) Nucleotides (44)Nucl. (44) Proteins (34)Prot. (34) Interactants (176)Interact. (176) Wiki
XB-GENEPAGE-854096
???displayGene.symbol???:
 pou1f1

???displayGene.name???: 
POU class 1 homeobox 1

???displayGene.synonyms???
GHF-3 , pit-1 , pit1 ( Nomenclature history )

???displayGene.geneFunction???
homeodomain transcription factor

AI Protein Function :
pou1f1 is a POU homeodomain transcription factor localized to the nucleus. It functions as a transcriptional activator of growth hormone, prolactin and thyroid‑stimulating hormone β genes in the pituit...[+]


InterPro :
Lambda DNA-bd dom sf, POU, POU dom, Homeobox dom, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
isolated growth hormone deficiency type II [+]

MIM:
PITUITARY HORMONE DEFICIENCY, COMBINED OR ISOLATED, 1; CPHD1

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info