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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (6)Lit. (6) GO Terms (12)GO (12) Nucleotides (75)Nucl. (75) Proteins (34)Prot. (34) Interactants (365)Interact. (365) Wiki
XB-GENEPAGE-852985
???displayGene.symbol???:
 fbxw4

???displayGene.name???: 
F-box and WD repeat domain containing 4

???displayGene.synonyms???
dac , fbw4 , fbwd4 , shfm3 , shsf3 [-] ( Nomenclature history )

???displayGene.geneFunction???
myosin heavy chain kinase

AI Protein Function :
fbxw4 encodes an F‑box protein that functions as part of an SCF E3 ubiquitin‑ligase complex, targeting specific substrates for proteasomal degradation and influencing cell‑cycle progression. The protei...[+]


InterPro :
WD40 repeat dom sf, WD40 repeat, WD40/YVTN repeat-like dom sf, F-box-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
split hand-foot malformation 3

MIM:
SPLIT-HAND/FOOT MALFORMATION 3; SHFM3

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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