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Summary Expression Expr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (41)GO (41) Nucleotides (133)Nucl. (133) Proteins (53)Prot. (53) Interactants (144)Interact. (144) Wiki
XB-GENEPAGE-6458028
???displayGene.symbol???:
 phlpp1

???displayGene.name???: 
PH domain and leucine rich repeat protein phosphatase 1

???displayGene.synonyms???
phlpp , plekhe1 , scop ( Nomenclature history )

???displayGene.geneFunction???
Serine/threonine phosphatase 2C containing leucine-rich repeats, similar to SCN circadian oscillatory protein (SCOP)

AI Protein Function :
phlpp1 encodes a protein phosphatase that dephosphorylates Akt and PKC isoforms, acting as a negative regulator of Akt signaling pathways. It is expressed in the developing brain, eye, heart, pronephro...[+]


InterPro :
Leu-rich rpt, Leu-rich rpt typical-subtyp, LRR dom sf, LRR domain-containing, [+]

???displayGene.geneInteractants???
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Diseases: 


External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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