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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (22)GO (22) Nucleotides (216)Nucl. (216) Proteins (70)Prot. (70) Interactants (78)Interact. (78) Wiki
XB-GENEPAGE-1002061
???displayGene.symbol???:
 herc1

???displayGene.name???: 
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

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( Nomenclature history )

???displayGene.geneFunction???
Uncharacterized conserved protein, contains RCC1 domain

AI Protein Function :
herc1 encodes a HECT‑type E3 ubiquitin‑protein ligase that mediates ubiquitination of substrates involved in vesicle trafficking and neuronal differentiation; the protein localizes to the cytoplasm, Go...[+]


InterPro :
WD40 repeat CS, B30.2/SPRY, ConA-like dom sf, RCC1/BLIP-II, [+]

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Diseases: 


MIM:
MACROCEPHALY, DYSMORPHIC FACIES, AND PSYCHOMOTOR RETARDATION; MDFPMR

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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