Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (5)Lit. (5) GO Terms (16)GO (16) Nucleotides (118)Nucl. (118) Proteins (28)Prot. (28) Interactants (79)Interact. (79) Wiki
XB-GENEPAGE-6469177
???displayGene.symbol???:
 mdc1

???displayGene.name???: 
mediator of DNA damage checkpoint 1

???displayGene.synonyms???
nfbd1 ( Nomenclature history )

AI Protein Function :
mdc1 encodes a nuclear DNA‑damage checkpoint protein that mediates ATM‑dependent signaling, promotes γ‑H2AX amplification, recruits RNF8 and other repair factors to double‑strand break sites, and facil...[+]


InterPro :
BRCT dom, BRCT dom sf, DDR Transcriptional Reg, FHA dom, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info