Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (29)GO (29) Nucleotides (66)Nucl. (66) Proteins (23)Prot. (23) Interactants (21)Interact. (21) Wiki
XB-GENEPAGE-6457748
???displayGene.symbol???:
 nsmce2

???displayGene.name???: 
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase

???displayGene.synonyms???
mms21 , nse2 ( Nomenclature history )

AI Protein Function :
nsmce2 encodes a SUMO E3 ligase that is a core component of the SMC5/6 DNA‑repair complex, mediating SUMOylation of target proteins during the DNA damage response, facilitating double‑strand break repa...[+]


InterPro :
Nse2(Mms21), Znf MIZ, Znf RING/FYVE/PHD

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
Seckel syndrome 10

MIM:
SECKEL SYNDROME 10; SCKL10

External Links:
Loading gene data...
Please wait while we fetch the latest information
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info