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Summary Expression Expr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (76)GO (76) Nucleotides (80)Nucl. (80) Proteins (46)Prot. (46) Interactants (69)Interact. (69) Wiki
XB-GENEPAGE-6451229
???displayGene.symbol???:
 btk

???displayGene.name???: 
Bruton tyrosine kinase

???displayGene.synonyms???
agmx1 , atk , bpk , imd1 , LOC108698274 , psctk1 [+] ( Nomenclature history )

AI Protein Function :
btk encodes a Tec family non‑receptor tyrosine kinase that functions as a signaling molecule in B‑cell receptor pathways, activating phospholipase C‑γ2, calcium influx and NF‑κB signaling; it is expres...[+]


InterPro :
SH2 dom sf, Ser-Thr/Tyr kinase cat dom, Tyr kinase AS, Protein kinase ATP BS, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
isolated growth hormone deficiency type III [+]

MIM:
AGAMMAGLOBULINEMIA, X-LINKED; XLA [+]

External Links:
1/2
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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